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Retail sales data are key to providing real-time information on the rapidly changing e-cigarette landscape, which is essential to reducing youth tobacco use. Retail sales data from Information Resources, Inc., which included Universal Product Code sales from brick-and-mortar retailers only, were analyzed by CDC, CDC Foundation, and Truth Initiative

This increased interest led to 100 scientific articles being published in the latter half of the nineteenth century on the therapeutic effects of cannabis [21], including a report on the isolation of the first cannabinoid (cannabinol [CBN]) in 1899 [22]