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[14] In response, Robin Sommers, the CEO and majority owner of Santa Fe Natural Tobacco Company, stated that "Native Americans are not a target market for American Spirit", stating that the use of this imagery was due to the company's goal to bring tobacco usage more in line with a perceived "moderation" by Indigenous peoples in the 15th century and that proceeds from sales support Native communities

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It is also used as an insecticide. Home Remedies for Nicotine Stain Removal from Walls The University of Georgia outlines a simple remedy for helping to remove nicotine stains from walls: using warm, sudsy water, after submerging a sponge or cloth, wipe the affected surface down, taking care to rinse and wipe it dry

By 2022, this figure has fallen to 15.6%