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The letters did not order Reynolds to recall its products, or explicitly threaten any fines or legal action against the company, but the notice could drastically cut into Reynolds sales because it would open up retailers to fines if they sell the products

In fact, over 5 million middle- and high-school students were current users of e-cigarettes in 2019 [75], and appealing flavours have been identified as the primary reason for e-cigarette consumption in 81% of young users [76]

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Cannabinoid compounds (see "Cannabis 101") interact with receptors in nerve cells to slow down pain impulses and ease discomfort