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Tobacco addiction during pregnancy increases the risk of miscarriage, premature birth, low birth weight, and congenital disabilities

In eight studies in which the effects of smoking cessation on endothelial function were assessed by biomarkers[19, 20, 23, 24, 30, 31, 92, 93], five studies showed that smoking cessation increased or improved biomarkers for endothelial function including circulating levels of nitrate/nitrite, NO, vvWF, ICAM-1, EPCs and EMPs and activity of eNOS [19, 23, 24, 30, 31]

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