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Subsequent research indicated that AMs from COPD patients exhibited impaired phagocytosis associated with mitochondrial dysfunction (80), possibly due to the decreased mitochondrial membrane potential, which caused cellular energy depletion, proton leakage, and overproduction of mtROS (89)

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Some authors claim that increase in the number of leukocytes can be the consequence of nicotine induced release of catecholamine and steroid hormones from the core of the adrenal gland

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