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A key factor shaping this market is its position as an alternative to traditional cigarettes, with some consumers perceiving smokeless tobacco as a less harmful substitute, particularly in regions with increasing public smoking bans and growing health awareness regarding combustible products

Acknowledgments The authors are thankful to the Director, CSIR-National Botanical Research Institute, Lucknow, for the facilities, and to the Indian Council of Medical Research, New Delhi, for a fellowship to K

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Short Term Effects Nicotine addiction Nicotine is the primary addictive substance in e-cigarettes