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There are already plenty of reasons to avoid both smoking and heavy drinking

While the positive outcomes suggest that the TWTQ program may be effective, controlled trials are needed to confirm these findings and isolate the specific contribution of each component of the intervention

This means the FDA still regulates the manufacture, import, labeling, packaging, advertisement, and distribution of all ENDs and their main components

These limitations highlight the necessity for future research to integrate clinical registration, causal inference methods, and dynamic modeling to improve risk assessment and provide information for targeted interventions