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As the effects of nicotine are felt quickly and dissipate rapidly, those with a physical dependence will often need high amounts of the substance to feel its effects

They are likely to have a relatively low-risk profile, similar to other forms of orally administered nicotine

Skoal had a long cut free nicotine level range of 1.7 mg [tied for 16th strongest level, (Skoal Long Cut Cherry)] to 3.9 mg of free nicotine per gram of tobacco [tied for 8th strongest level (Skoal Long Cut Straight) and (Skoal Fine Cut Original)]

Although a smaller percentage of American men smoke today than thirty years ago, a greater percentage of smokers are women and teenagers