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Dimensions: 5760 x 3840 px | 48.8 x 32.5 cm | 19.2 x 12.8 inches | 300dpi Date taken: September 2013 Photographer: Zoonar/Wavebreak Media LTD More information: Hand putting out a cigarette in ashtray on black background

Therefore, smoking cessation provided a protective effect against developing UC

doi: 10.1016/j.jclinepi.2017.12.008 21

Images were analyzed using standard preprocessing procedures (slice time-corrected, motion-corrected, resampled to 3 3 3 isotropic voxels, normalized to Montreal Neurological Institute space, spatially smoothed using a 6-mm FWHM Gaussian filter, and temporally filtered using a high-pass filter with 1/120 Hz cutoff frequency)