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Is Vaping a Gateway into Smoking
Taken together, DNA methylation at any given CpG is the result of multiple processes that are orchestrated as a developmental cascade involving, first, global demethylation after fertilization, then, cell/tissue-specific re-methylation during very early embryogenesis and, finally, maintenance of DNA methylation throughout the remainder of life
In brief, RETUNE includes participants aged 18 years, who signed the general SHCS randomization consent and smoke at least one tobacco cigarette per day