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Mechanism of Action GHRP-6 is a full GHSR-1a agonist and, structurally, the closest analogue among these three to endogenous ghrelin

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They suggested ghrelin for the octanoyl-modified peptide, desacyl-ghrelin for the non-acylated version, GHSR for the ghrelin receptor and liver-expressed antimicrobial peptide 2 (LEAP2), and LEAP2 for the newly identified endogenous GHSR antagonist/inverse agonist (25)

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