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In addition, GLP-1 can reduce liver cholesterol accumulation by inhibiting SREBP2 and PCSK9, and reduce liver bile acid synthesis by weakening the negative feedback inhibition of bile acid after inhibiting FXR

GLP-1 Antidiabetic Medication NAION Vision Loss Study The recent study published in medical journal, JAMA Ophthalmology, examined vision loss or blindness in people who took GLP-1 antidiabetic medication

Clinical Trial Protocols Clinical studies of Retatrutide have so far followed a once-weekly subcutaneous injection model, mirroring the approach used with other GLP-1 receptor agonists like semaglutide and tirzepatide