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Notably, choline transporter-like proteins (CTLs), especially CTL1 (SLC44A1) and CTL5 (SLC44A5), mediate high-affinity choline uptake in oligodendrocytes, a process essential for the biosynthesis of choline-derived plasmalogens (Traiffort et al., 2013)

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Healthcare professionals managing such patients should document the rationale for both medications, monitor for adverse effects, and regularly review the necessity of continuing both treatments

Therefore, doctors recommend taking it on an empty stomach in the morning to increase its absorption and interaction with meals