For the electron coupling assays, respiratory substrates (10 mM pyruvate + 2 mM malate, 10 mM succinate + 2 M rotenone, 80 M palmitoyl-carnitine or octanoyl-carnitine + 0.5 mM malate or 10 mM glutamate + 10 mM malate) were diluted in MAS buffer with BSA (70 mM sucrose, 220 mM mannitol, 10 mM KH 2 PO 4 , 5 mM MgCl 2 , 2 mM HEPES and 1 mM EGTA, pH 7.2, in 0.2% FA-free BSA) and added to mitochondria
More research is needed on how GLP-1 RAs affect electrolyte balance (and its likely highly individual depending on each persons unique circumstances), but the topic deserves attention given hydrations role in metabolic health
Increased Bone Density Maintaining strong and healthy bones is essential for preventing osteoporosis and reducing the risk of fractures, especially as we age
The difference often comes down to how the compound is delivered and how much of it your body can actually use