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Thyroid function monitoring: Thyroid function tests (TFTs) measuring thyroid-stimulating hormone (TSH) and free thyroxine (FT4) should be checked regularly, particularly when starting or adjusting levothyroxine therapy
( a-d ) Representative histological images of in situ hybridization for DAPI (blue), Glp1r (magenta), Gnas (green) Glp1r-ires-cre mouse (n = 4 mice) ( a-b ) or Glp1r-ires-cre:Gnas fl/fl mouse (n = 4 mice) ( c-d )
A p-value of less than 0.05 was set as the threshold for clinical significance
If your weight is dropping but your lean mass is holding steady, the protocol is working as intended
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