This drug reduces the efficacy of the natural TNF molecule by acting as a decoy receptor that binds to TNF [150], and dull the immune response
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S., Khanlarkhani, N., Khezri, Z., Majidpoor, J., Abouzaripour, M., Habibi, M., Kashani, I
Experimental data showed that 10 M resveratrol completely inhibited the release of the inflammatory mediator IL-6, while resveratrol-3-sulfate and resveratrol-disulfate decreased by 84.2 29.4% and 52.3 39.5%, respectively, and the release of TNF- was reduced by 48.1 15.4%, 33.0 10.0%, and 46.7 8.7%, respectively, in macrophage assays in vitro 60