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Patients frequently seek medical attention only after symptoms substantially impair quality of life, by which point tissue injury may be established, such as lupus nephritis in SLE, pericarditis in RA, or thromboembolic complications in Crohns disease [25, 26]

The presence of these other types of crystal-related inflammation further emphasizes the value of identifying uric acid crystals as the cause of a particular patients arthritis whenever possible, to insure that the correct condition is being treated

Lutchman, G

Serum samples were collected at different intervals postinfection to monitor temporal Pb SLTRiP expression dynamics via ELISA