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Seek medical attention if you experience: Muscle spasms that last longer than a few days Severe pain or weakness in the affected area Swelling, redness, or warmth in the affected muscle Difficulty moving the affected limb Muscle spasms that occur frequently or interfere with daily activities Muscle spasms accompanied by other symptoms such as fever, numbness, or tingling Your doctor can help determine the underlying cause of muscle spasms and recommend appropriate treatment options (Bordoni et al., 2023)

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Selectivity profiling indicates activity on ERRs with minimal cross-activation of classical ER/ER or unrelated nuclear receptors at concentrations relevant to the ERR program

Although the various DOACs were linked to similar risks of bleeding events overall, rivaroxaban was associated with a lower rate of intracranial bleeding, but a higher rate of gastrointestinal bleeding, compared with apixaban