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At the insistence of its members, the American Society of Anesthesiologists recommended halting GLP-1s at least 1 week prior to any elective surgery that requires sedation

It has been found to improve memory, attention, and mental performance in elderly individuals (3)

Knowing your genetic predisposition before considering combination therapy allows your provider to distinguish between truly inadequate response to semaglutide monotherapy versus suboptimal dose, lifestyle factors, or adherence issues

Whilst generally well tolerated, allergic reactions to tirzepatide injection can occur, ranging from mild local injection site reactions to severe systemic hypersensitivity