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Allergy Asthma Clin Immunol 12:114 Bissonnette R, Pavel AB, Diaz A, Werth JL, Zang C, Vranic I, Purohit VS, Zielinski MA, Vlahos B, Estrada YD (2019) Crisaborole and atopic dermatitis skin biomarkers: an intrapatient randomized trial

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30 min pretreatment, followed by 24 h AO exposure) dose-dependently inhibits the release of proinflammatory mediators (TNF-, IL-1, NO) induced by AO in primary mouse microglia, suppresses oxidative stress, and restores the antioxidant capacity of cells [5]