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In patients with liver impairment or decreased hepatic blood flow including the elderly, those experiencing cardiogenic shock, heart failure, myocardial infarction, or those taking cimetidine and beta-blockers lidocaines plasma levels increase, and its half-life extends (51)

doi: 10.1155/2015/628157 PMCID: PMC4637104 Intestinal Permeability in Inflammatory Bowel Disease: Pathogenesis, Clinical Evaluation, and Therapy of Leaky Gut Andrea Michielan and Renata DInc ~ Therap Adv Gastroenterol

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