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Secondly, androgen therapy was recommended to improve penile length for micropenis 9,12,15,19,21,22 but not for normal individuals, more attention should be paid to clarify the unclear underlying mechanism

433 Methylglyoxal, a reactive dicarbonyl by-product of glycolysis, induces post-translational modifications of the voltage-gated sodium channel Nav1.8, increasing the excitability of nociceptive neurons

By simultaneously activating incretin and glucagon pathways, it influences central satiety circuits and peripheral metabolic processes