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Preclinical studies suggest that statins can reduce BBB permeability by enhancing the expression of tight junction proteins and decreasing the activity of MMPs, which are implicated in the degradation of tight junctions (Liu et al., 2021)

Gastrointestinal symptoms and fecal shedding of SARS-CoV-2 RNA suggest prolonged gastrointestinal infection

The biological mechanism (localized melanin accumulation) is identical, which is why the corrective approach is also the same

While these medications won't replace CPAP therapy for everyone, they offer new hope for millions struggling with both excess weight and disrupted sleep