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More data could be available soon, however

(1985): DSIP administration modulated cortisol and ACTH secretion in human subjects, demonstrating the peptide's interaction with the HPA axis

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Post hoc analysis of LEADER data revealed a persistent increase in the overall risk of biliary tract-related events and gallbladder diseases, consistently observed across four categories: uncomplicated gallbladder stones, complicated gallbladder stones, cholecystitis with/without gallbladder stones, and biliary obstruction [34]