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In conclusion, the evidence from multiple studies confirms that the long-term efficacy of bariatric surgery in MC4R -deficient obesity is limited, which is closely related to the type of MC4R mutation (homozygous vs

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Second, prospective cohorts with complete staging, dosing, duration, and adherence data, integrated with tumor genomics, systemic biomarkers, and patientreported outcomes to dissect mechanisms and identify responsive subgroups, he continued

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doi: 10.1046/j.1471-4159.1998.71052071.x

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