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Intragastric gavage of FAHF-1 (21 mg/mouse) inhibited peanut-induced anaphylaxis and peanut specific (s)-IgE by 2 weeks of treatment that persisted over 4 weeks post-therapy [32]

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In cardiac cells, the physical proximity between mitochondria and the sarcoplasmic reticulum (SR, a specific type of ER in heart and skeletal muscle cells) allows the exchange of Ca 2+ in local microdomains, providing rapid Ca 2+ buffering