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Current clinical treatment guidelines aim for a functional cure for CHB, which involves sustained negativity for hepatitis B surface antigen (HBsAg), undetectable HBV DNA, normal liver biochemical indicators, and improvement of liver tissue lesions after treatment cessation

Conclusion There is little convincing evidence in favor of glutathione as a therapy for hyperpigmentation at the present time, and there are many unresolved controversies that surround its use (Figure 5)

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