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The 1 H-fMRS voxel was positioned in an ACC region-of-interest (20 mm 20 mm 20 mm) with the center of the voxel placed 16 mm above the most anterior portion of the genus of the corpus callosum, perpendicular to the anterior commissureposterior commissure line to minimize inclusion of white matter and cerebral spinal fluid (Supplementary Fig

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Food and Drug Administration or the European Medicines Agency for any indication

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