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For example, antibiotics that induce ROS, like -lactams or aminoglycosides, often cause bacteria to up-regulate the pentose phosphate pathway for NADPH production, which feeds GSH

USA 2002;99:1876-81

Embryo-Fetal Toxicity Inform patients who can become pregnant that QSYMIA can cause fetal harm and patients should avoid getting pregnant while taking QSYMIA [see Warnings and Precautions (5.1), Drug Interactions (7), and Use in Specific Populations (8.3)]

Safety data from over 900 clinical trial participants demonstrates that AOD-9604 is remarkably well-tolerated with a side effect profile indistinguishable from placebo in most studies