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Rutgeerts P, Sandborn WJ, Feagan BG, Reinisch W, Olson A, Johanns J et al

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Users who haven't seen significant improvement by week 12 may need protocol adjustment: higher concentration, different product format, or combination with other treatments

Calibration Standards for the amount of Niclosamide in solution versus pH S3.1 Experimental Calibration standards (of 20uM, 50uM, 100uM, 150uM, 200uM, 250uM and 300uM) for the UV/Vis experiment were prepared by injecting 100uL of each ethanolic niclosamide solution into 10 mLs of the 9.3 pH buffer giving a 1:99 dilution and a final 1% ethanol solution of niclosamide