M., Sanna, E., Deiana, L., Panzone, F., Contu, P., and Floris, C
Am J Clin Nutr 113(2):314323
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Briefly, protein aggregates should bind to the HSP70-HSP40 complex and p97, a powerful ATPase, at the same time and then be recognized by TAX1BP1 and routed into aggrephagosomes (Krner et al., 2025)