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Tran D, Tran PA, Tang YQ, Yuan J, Cole T, Selsted ME: Homodimeric -defensins from Rhesus macaque leukocytes: isolation, synthesis, antimicrobial activities, and bacterial binding properties of the cyclic peptides

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Although the specific mechanisms underpinning ketamines antidepressant actions are yet to be fully determined, one hypothesis proposes that ketamine preferentially blocks NMDA receptors expressed on -aminobutyric acid (GABA) interneurons, leading to disinhibition of pyramidal neurons and increased glutamate release 3