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First, we verified that in the plasma of female mice with fibrosarcoma invasion, a typical example of NRTP, CXCL10 was the primary pro-inflammatory cytokine that is detrimental to the ovaries

Published Research on 5-Amino-1MQ Foundational DIO Mouse Study Neelakantan et al., Biochemical Pharmacology (2018) This paper introduced 5-Amino-1MQ as a selective and membrane-permeable small molecule inhibitor of NNMT and tested it in 3T3-L1 adipocytes and in male C57BL/6J mice maintained on a high-fat diet

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Mini Rev Med Chem 6: 16376