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3 , 84ra44 (2011)

No study has systematically examined whether iron overload drives senescence and fibrosis, or if senescence worsens iron retention and chronic inflammation

At the end of treatment, mice were euthanized by asphyxiation with CO 2 and peripheral blood, spleen single cell population were analyzed for the ROS, ferroptosis levels by DCF and Bodipy-C11 staining followed by flow cytometry analysis

However, the process of collecting and storing blood samples involves several decisions that can alter profiles of biological analytes, thus serving as potential confounds in analysis