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Exendin-4 restores airway mucus homeostasis through the GLP1R-PKA-PPARgamma-FOXA2-phosphatase signaling

Since 2022, the American Diabetes Association has updated its Standards of Care to recommend GLP1 receptor agonists as a firstline therapy for T2D 2 , eroding older and cheaper generics like metformin, which marks a momentous and fundamental change in treatment