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The consequences of muscle mass loss during GLP-1-induced weight loss include reduced resting metabolic rate making weight regain more likely if the medication is stopped reduced functional strength and physical capacity, increased falls risk in older adults, reduced bone density, and the loss of the metabolic benefits that muscle tissue provides including improved insulin sensitivity and glucose uptake

YL: Supervision, Writing original draft

This reflects the biological chronicity of obesity: the hypothalamic set-point for body weight, appetite hormone profiles (including leptin and ghrelin), and resting metabolic rate tend to revert toward pre-treatment baselines once pharmacological GLP-1 stimulation is removed

But even as careful as I have been, clearly I wasn't careful enough