However, their mechanism of action presents unique physiological hurdles that can derail athletic performance if not managed correctly.[2][3] The Mechanism: Why It Matters for Sport GLP-1 agonists work primarily by mimicking a hormone that targets areas of the brain that regulate appetite and food intake
Identifying Your Baseline Metabolic Response Before considering fasting on GLP-1 medication, assess your individual tolerance on the medication alone
van Bruggen R, Bautista JM, Petropoulou T, de Boer M, van Zwieten R, Gmez-Gallego F, et al
It activates specific signaling molecules such as protein kinase B (Akt) and mammalian rapamycin target protein (mTOR), which can further regulate gene expression, promote protein synthesis in muscle cells, and promote muscle fiber growth