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Creatine in older adults Much of the creatine research relevant to semaglutide users comes from studies in older adults, a population that shares key similarities with GLP-1 users: they are prone to muscle loss, often have reduced protein intake, and benefit enormously from resistance training but may struggle with training intensity

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Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for the treatment of type 2 diabetes mellitus (under brand names Ozempic and Rybelsus) and chronic weight management (Wegovy)