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Leptin also triggers immune responses and induces other inflammatory mediators [21]

Although corticosteroids were considered as the first intralesional medication in PD, early published studies, including retrospective analyses and RCTs, have had mixed findings (Lamprakopoulos et al., 2000)

Consider eating smaller, more frequent meals to provide a steady stream of nutrients rather than experiencing energy peaks and crashes

These mechanisms can trigger headaches through several pathways: rapid changes in blood glucose levels, shifts in fluid and electrolyte balance due to reduced food intake, and activation of GLP-1 receptors in blood vessels and the nervous system