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Moderate = encouraging but limited or inconsistent human data

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Journal of the American Society of Nephrology: JASN 25 , 13871400, doi: 10.1681/ASN.2014010117 (2014)

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Liraglutide ameliorates cognitive decline by promoting autophagy via the AMP-activated protein kinase/mammalian target of rapamycin pathway in a streptozotocin-induced mouse model of diabetes

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If regression occurs during break, may need additional treatment cycle

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