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The precise mechanism involving GPX4-induced SSMD remains to be discovered, although it is established that a complete loss of enzymatic GPX4 activity is a central component to the clinical phenotypes of SSMD patients

Am J Enol Viticult 49:240250 Matsufuji Y, Fujimura S, Ito T, Nishizawa M, Miyaji T, Nakagawa J, Ohyama T, Tomizuka N, Nakagawa T (2008) Acetaldehyde tolerance in Saccharomyces cerevisiae involves the pentose phosphate pathway and oleic acid biosynthesis

(More information) Products of animal origin constitute the primary source of vitamin B 12