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However, the largest Phase IIb trial involving 536 subjects failed to demonstrate statistically significant weight loss compared to placebo at the primary 12-week endpoint, leading Metabolic Pharmaceuticals to terminate development in 2007
In SURMOUNT-1, nausea occurred in 24.6% of participants on 5mg, 33.3% on 10mg, and 31.0% on 15mg
Methionine is a lipotropic, or a chemical substance that helps the liver process fats (lipids)
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