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A brand called Supergut touts prebiotics as natures Ozempic in its marketing and claims that its products trigger your bodys hunger-quieting GLP-1 hormone naturally. The supplement brand Pendulum offers a GLP-1 Probiotic, which it also claims helps increase GLP-1 production naturally. Other lines, like Codeage, offer blends like the GLP Advantage+, which contains L-taurine, decaffeinated green tea leaf extract, boron, prebiotics, and a variety of other ingredients, including berberine, an antibiotic-like ingredient popular with wellness influencers on TikTok who tout its appetite-suppressing properties

longer-term safety in that group is not fully established

6.2 Postmarketing Experience Additional adverse reactions have been identified during postapproval use of JANUMET, sitagliptin, or metformin

Identifying relevant PROMs can inform clinical trial design for targeted and personalized interventions