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Although there is no absolute contraindication to using both medications together, their opposing metabolic effectsparticularly on appetite, weight, and blood glucoserequire careful monitoring and individualised management

Wu J, Tang Q, Ren X, Zheng F, He C, Chai X, Li L, Hann SS (2019) Reciprocal interaction of HOTAIR and SP1 together enhance the ability of Xiaoji decoction and gefitinib to inhibit EP4 expression

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