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Diarrhea is another commonly reported gastrointestinal side effect that may range from mild loose stools to more significant episodes that could lead to fluid and electrolyte imbalances if severe or prolonged

HFD impairs liver glutathione biosynthesis, vitamin D metabolism genes and genes associated with non-alcoholic fatty liver disease (NAFLD) Genes involved in the GSH biosynthesis pathway were significantly downregulated in the livers of mice fed an HFD compared to those of mice fed a healthy diet (controls) (Fig

Mitochon- drial GPx4 transcripts were normalized on 18S rRNA levels using the primer pair (Oligo18Sfor1: 5-GGACAGGATTGA- CAGATTGATAG-3/Oligo18Srev1: 5-CTCGTTCGTTATCG- GAATTAAC-3)

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