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As summarized in Table 2, these finding highlights the therapeutic potential of polyphenols in addressing AD and other NDDs, offering

For inhalation therapy, drug particle size is considered the most important parameter since drugs should reach the entire bronchial tree and in particular the small airways (or bronchioles)

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Persistent mild inflammation directly leads to disorders of blood glucose regulation and exacerbates complications such as diabetic nephropathy, cardiovascular diseases, and retinopathy through mechanisms such as impairing the function of pancreatic islet cells, aggravating reduced sensitivity to insulin, and promoting vascular endothelial damage (Figure 3)