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netBRET was determined by subtracting the ratio measured from cells expressing only the BRET donor from cells expressing the BRET donor and acceptor

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The enhanced mitochondrial oxidative stress leads to DA oxidation with generation of DAQs, conjugation of DAQs with GBA1, inhibition of GBA1 enzymatic activity, lysosomal dysfunction, and accumulation of deleterious -syn protein [10]

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Renal, Cardiovascular, and Safety Outcomes of Canagliflozin by Baseline Kidney Function: A Secondary Analysis of the CREDENCE Randomized Trial

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doi: 10.1097/TP.0b013e31826e592e

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