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The catch is that your body cant store these vitamins for later use, meaning you need a more frequent intake to ensure you arent deficient in water-soluble vitamins

Metformin dosages were dynamically adapted every week in response to the fluctuations in mouse body weight

Spectra were acquired on a Varian Inova NMR spectrometer (Agilent Technologies Inc., Santa Clara, CA, USA), equipped with a triple resonance probe and operating at a resonant frequency of 1 H at 500 MHz and a constant temperature of 25C