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These studies suggest a possible interorgan crosstalk including brain-BAT-heart that is modulated by LepR activation in the CNS, and this may constitute a novel target for therapies to protect the heart against ischemic insults

Pekun, T.G., Hrynevich S.V., Waseem, T.V., and Fedorovich, S.V., Role of iron, zinc and reduced glutathione in oxidative stress induction by low pH in rat brain synaptosomes, SpringerPlus , 2014, vol

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