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Autism: a mitochondrial disorder

Proper peptide storage and handling prove essential, with lyophilized peptides requiring storage at -20C or lower (optimally -80C) away from bright light and moisture, and peptides containing cysteine, methionine, or tryptophan requiring additional protection from oxidation through anaerobic storage conditions to maintain stability and biological activity throughout experimental protocols

The recycling of citrulline back to l-Arg via ASS/ASL (the citrulline-NO cycle) pathway sustains NO production even under low plasma l-Arg availability [120]

Bariatric surgery may be considered for eligible patients with severe obesity according to NICE obesity guidance and can lead to significant improvements in NASH and fibrosis